Placental Lactogen, Human (hPL)
Scripps Laboratories is a world-leading producer and supplier of purified human Placental Lactogen (hLH). Please use the link below to view more information and product specifications.
The human placenta produces several hormones that are homologous to hormones of the anterior pituitary. One of those, Human Placental Lactogen (hPL), is a single polypeptide chain of 190 amino acid residues and is structurally similar to human prolactin and growth hormone. Not surprisingly, hPL demonstrates both lactogenic and growth-stimulating activity.
hPL serum levels rise very early in normal pregnancy and continue to increase until a plateau is reached at approximately the 35th week post-conception. As such, immunoassays for maternal serum levels of hPL are useful in monitoring placental function. In addition, serum elevations of hPL in non-pregnant individuals are associated with various malignancies.
This preparation of hPL is isolated from human placenta and is provided as a powder, lyophilized from ammonium bicarbonate. Protein content is determined by absorbance at 280nm (Emg/ml = 0.90).
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