Protein A

Scripps Laboratories is a world-leading producer and supplier of purified Protein A. Please use the link below to view more information and individual product specifications.

Protein A is well known for its ability to bind the Fc fragment of most mammalian immunoglobulins especially IgG. This material is a polypeptide surface receptor isolated from the cell membranes of staphylococcus aureaus. It contains four nearly homologous regions and can bind two immunoglobulin molecules. Protein A binds immunoglobulins without interfering with the antigen binding sites which allows the formation of ternary complexes consisting of Protein A, antibody, and antigen. These properties make Protein A useful as a ligand for the affinity purification of monoclonal and polyclonal antibodies and in various immunoassays.

Protein A (cat. no. P0814) is purified from staphylococcus aureus and supplied as a lyophilized solid. The material exhibits >95% binding to human IgG agarose.

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