Troponin I, Human (cardiac muscle)

Troponin I (TnI), the inhibitory subunit of the troponin complex, exists in three distinct isoforms: cardiac muscle, fast-twitch skeletal muscle, and slow-twitch skeletal muscle. The cardiac isoform is approximately 40% dissimilar from the skeletal muscle isoforms and contains 31 N-terminal amino acids not found in the skeletal muscle isoforms.

This preparation of TnI is derived from human cardiac muscle and is supplied as a liquid in 75mM Tris, 10mM EGTA, 8M Urea, 60mM β-mercaptoethanol, 1mM Calcium Chloride, 1mM Benzamidine, pH 8.0 ± 0.1.

Companion Products:

• Troponin C (human cardiac muscle)
• Troponin C (rabbit skeletal muscle)
• Troponin I-C Complex (human and rabbit source)