Creatine Kinase (CK) is a dimeric enzyme composed of either M- or B-type subunits. The subunits, each encoded by a unique gene, associate to form three isoenzymic forms: BB, MB, and MM. These isoenzymes are expressed at different levels in various tissues in humans. CK-BB is predominantly found in brain tissue, CK-MB in heart muscle, and CK-MM in skeletal and heart muscle.
Scripps Laboratories offers highly purified, and highly active, CK-BB, CK-MB, and CK-MM, as well as antibodies to each isoenzyme: CK-BB monoclonal, CK-MB monoclonal, CK-MM monoclonal and CK-MM goat polyclonal.
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