Carcinoembryonic Antigen (CEA)

Carcinoembryonic Antigen (CEA) is a glycoprotein expressed in a variety of secretory tissues. CEA is thought to be involved in intercellular recognition and attachment in the development and proliferation of various metastases. Elevated serum levels of CEA are associated with several malignant states, and immunoassays for CEA have been used for several years in monitoring many such malignancies.

CEA preparations from Scripps Laboratories are derived from either human tissue/fluids (native) or a human colon carcinoma cell line. Native CEA is supplied as a liquid in either 10mM Potassium Phosphate, 100mM Sodium Chloride, pH 7.2 - 8.2, containing 0.1% Sodium Azide (C0222) or 10mM Tris, pH 8.0 ± 0.1, containing 0.1% Sodium Azide (C0223 & C0224). The cell culture form is supplied as a powder lyophilized from PBS containing 0.1% Sodium Azide. Specific protein is determined by immunoassay. Purity is determined by SDS-PAGE or estimated by the CEA/Total Protein ratio.

Please note that a CEA Monoclonal antibody is also available.

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